Abstracts and Articles on Api-Virology

CORONAVIRUS

Propolis against coronavirus

Populus spp. type of propolis

 

Bacharis dracunculifolia type of propolis

Propolis against ACE2 receptors (2020) (Turkey)


PAK1-blockers Potential Therapeutics against COVID-19 (2020)(Australia)


Withanone and Caffeic Acid Phenethyl Ester against SARS CoV 2 (2020) (India, Japan)


Propolis, melatonin, artemisinin and other substances as PAK1-blocking Therapy of Pandemic Coronaviral Infection (2020) (Australia)


Benzyl alcohol against syncitial virus, influenza A and SARS-CoV (2005) (UK)


Effects of propolis flavonoids on virus infectivity and replication (1990, Italy)


Quercetine against SARS (2006)(China)


Torreya nucifera, apigenine, luteoline and quercetine against SARS virus (2010)(Korea)


AntiSARS and anti Hepatitis C Virus effects of quercetin (2012, Korea)


Polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors


In Silico approach of some selected honey and propolis constituents as SARS-CoV-2 main protease (COVID-19) inhibitors (2020) (Egypt)


 

Bee venom against coronavirus

 

 

 

 

 

Bee venom and Covid-19 in China (over 5000 beekeepers, no death) (2020)(China)


Abstract – Effect of Melittin and Apamin Co-therapy on the Inhibition of Coronavirus Cell Mediated Entry- A Potential management of Covid-19


 

Honey against coronavirus

In Silico approach of some selected honey and propolis constituents as SARS-CoV-2 main protease (COVID-19) inhibitors (2020) (Egypt)


Nigella sativa (black cumin) and honey against COVID-19 (2020)(Saudi Arabia, Egypt)


Essential oils (from medicinal bee plants) against coronavirus

Antiviral essential oils (2020) (Algeria)

HIV (AIDS)

Bee venom and its melittin against HIV

 

 

 

 

 

 

Melittin: a venom-derived peptide with promising anti-viral properties – Hamed MemarianiMojtaba MemarianiHamideh MoravvejMohammad Shahidi-DadrasEuropean Journal of Clinical Microbiology & Infectious Diseases volume 39pages 5–17 (2020)


Melittin against Nef and HIV


Melittin as antiviral agent (2020)(Iran)


Melittin, chrysine and other natural compounds against HIV (2001)(France)


Phospholipase A2 against HIV (2001)(France)


Venom proteins against HIV


Nanoparticle Incorporation of Melittin Reduces Sperm and Vaginal Epithelium Cytotoxicity (2014) (USA)


 

Propolis and its substances against HIV


Antiviral properties of caffeic acid phenethyl ester and its potential application (2015) (Turkey)


Anti AIDS propolis compounds (Prof. Park)


Anti-HIV-1 activity of propolis in CD4+ lymphocyte and microglial cell culture (2005) (USA)


CAPE against nuclear transcription factor NF-kappa B (1996) (USA)


 

Bee pollen against HIV

 

NAC against HIV (1991) (Germany)


Tertiary alcohols against HIV (Sweden)


Cysteine against HIV and inflammation (1991) (Germany)


 

Honey against HIV

Tualang honey ameliorates viral load, CD4 counts and improves quality of life in asymptomatic human immunodeficiency virus


 

HERPES

Propolis against Herpes

Mucoadhesive green propolis formulation against herpes simplex virus type 1 skin lesions (2016) (Brazil)


Green propolis against Suid herpesvirus type 1 (2006) (Brazil)


Green propolis against herpes virus type 5, as co-vaccine (2007) (Brazil)


Effects of propolis flavonoids on virus infectivity and replication (1990, Italy)


Propolis and honey in the treatment of blister-like lesions around the mouth, skin and genitalia caused by herpes viruses-A systematic review (2019) (Germany)


Limonene (present in propolis too) against herpes virus (2014) (Iran, Germany)


Screening for Antiviral Activities of Isolated Compounds from Essential Oils (2009) (Germany-Iran)


Propolis extract against herpes labialis, clinical study (2011)(Czech Republic)


Propolis vs. Acyclovir against herpes labialis (2018)(Czech Republic + Germany)


Antiviral activity of Hatay Propolis against Herpes virus (2016)(Turkey)


Efficacy in the treatment of cervical HRHPV infection by combination of beta interferon, and herbal therapy in woman with different cervical lesions


A comparative multi-centre study of the efficacy of propolis, acyclovir and placebo in the treatment of genital herpes


Treatment of cutaneous herpes and herpes zoster with Nivcrisol-D


Propolis against varicella zoster virus (2018) (Poland)


Olive leaf, propolis extracts and acyclovir against herpes simplex virus type 1 (Turkey)


 

Essential oils and their compounds against herpes virus

Thymol, carvacrol, p-cimene (present in propolis too) and other monoterpenes against herpes virus (2017) (Iran, Germany)


Volatile substances from essential oils against herpes virus (2010) (Germany)


 

Bee venom against herpes

 

 

 

 

 

Bee venom treatment for refractory postherpetic neuralgia: a case report


Melittin against herpes virus (2000)(USA)


 

Honey against herpes

Propolis and honey in the treatment of blister-like lesions around the mouth, skin and genitalia caused by herpes viruses-A systematic review (2019) (Germany)


Honey vs. Acyclovir against herpes simplex labialis and genitalis (2004) (Dubai)


Honey, Royal jelly and Acyclovir against herpes virus (2014) (Iran)


Honey-against-varicella-zoster-virus (2012) (USA, Austria)


 

Bee pollen against herpes

Antiviral effect of brassinosteroids against herpes virus and arenaviruses (2000) (Argentina)

 


Royal jelly against herpes


Honey, Royal jelly and Acyclovir against herpes virus (2014) (Iran)


 

 

FLU (INFLUENZA)

Propolis against flu 

Effect of quercetin supplementation on lung antioxidants in experimental influenza infection (2005)(India)


Anti-Influenza Effects in Brazilian Green Propolis Water Extract


Anti-influenza virus activity of propolis in vitro and its efficacy against influenza infection in mice

3,4-Dicaffeoylquinic Acid, a Major Constituent of Brazilian Propolis, Increases TRAIL Expression and Extends the Lifetimes of Mice Infected with the Influenza A Virus


Benzyl alcohol against syncitial virus, influenza A and SARS-CoV (2005) (UK)


Caffeoylquinic acids are major constituents with potent anti-influenza effects in Brazilian green propolis water extract


Anti-influenza virus activity of propolis in vitro and its efficacy against influenza infection in mice



Parainfluenza virus type 3 and cytomegalovirus

Benzyl alcohol against respiratory viruses parainfluenza type 3 and cytomegalovirus (2015) (UK)


 

Bee venom against flu

 

 

 

 

Perspective of Use of Antiviral Peptides against Influenza Virus


Inhibitory effects of bee venom and its components against viruses in vitro and in vivo.


 

Bee pollen against flu

Neuraminidase Inhibitors from Papaver rhoeas pollen against influenza (2016) (Korea)



RHINOVIRUSES
(common cold causing viruses)

Propolis and its substances against Rhinoviruses

Propolis nasal spray against infectious acute rhinitis in children (2017) (Spain)


Benzyl alcohol against rhinoviruses (2016)(Korea)

 


Effect of dietary supplement containing Brazilian propolis on the common cold (abstract)(2010)(Japan)


Propolis aqueous extract against rhinopharyngitis in children (1995)(Romania)


 

ADENOVIRUS

Propolis against adenovirus

Effects of propolis flavonoids on virus infectivity and replication (1990, Italy)



ROTAVIRUS

Propolis against rotavirus

Effects of propolis flavonoids on virus infectivity and replication (1990, Italy)


 

RUBELLA virus

Effect of honey versus thyme on Rubella virus survival in vitro (1996) (Syria)


 

General articles

Propolis

Phenolic Profile, Antioxidant Capacities and Enzymatic Inhibitory Activities of Propolis (2020)(Spain)

Propolis blocks the ACE receptors which are important for the penetration of viruses in the cells/vascular system


Effects of propolis flavonoids on virus infectivity and replication (1990, Italy)


Antimicrobial, antifungal and antiviral substances from various types of propolis (2017)(Poland)


Immune activation and radioprotection by propolis


Immunomodulatory action of propolis. VI. Influence of a water soluble derivative on complement activity in vitro


Immunomodulatory Properties of Green Propolis


Propolis and the immune system. A review. JM Sforcin (2007)(Brazil)


Propolis induces Ca2+ signaling in immune cells


Quercetin against porcine epidemic diarrhea virus (2011) (Korea)


Geopropolis from Scaptotrigona postica as anti herpes virus (2015)(Brazil)


 

Bee venom and its components as direct and indirect antiviral agent

Melittin, a venom-derived peptide with promising anti-viral properties (2019) (Iran)


Bee Venom – Overview of Main Compounds and Bioactivities for therapeutic interests (2019 (Lebanon, France)


Cytolytic nanoparticles with melittine attenuate HIV-1 infectivity (2013(USA)


Bee venom and its components against viruses (2016) (Korea, Bangladesh)


Melittin against hepatocarcinoma (2015) (China)


Antiviral peptides against influenza viruses (2015) (Slovakia and Czech Republic)


Induction of IFN-γ cytokine response against hepatitis B surface antigen using melittin (2014) (Iran)


 

Honey and its direct and indirect role against viruses

 

Bee products against herpes virus (Munstedt Karsten)(2019)


Volatile Compounds in Honey. Christy E. Manyi-Loh et al. (South Africa)(2011)


 

Canine Distemper Virus

Mexican Propolis and three commercial Flavonoids against Canine Distemper Virus (2018) (Mexico)


 

Avian Leukosis Virus Subgroup B

Polysacharides from Pollen against chicken virus (2018) (China)

 


Bee pollen against inflammation

Cysteine against HIV and inflammation (1991) (Germany)


Beta-carotene against inflammation (2005) (Korea)


 

Immune System and Beehive Products

Immune System and Propolis

Immunomodulation potentials of propolis (2019) (Saudi Arabia)


Wound healing. Time to look for intelligent approaches (2017) (France)


Immunomodulatory Properties of Green Propolis (2014) (Brazil)


Immune activation and radioprotection by propolis (2005) (Japan)


Immunomodulatory action of propolis. VI. Influence of a water soluble derivative on complement activity in vitro (1995) (Bulgaria)


Efficiency of Propolis and N-a cetylcisteine on Reductionin Symptom Severity of Respiratory Infection in Children with Adenoid Hypertrophy


 

Immune System and Bee Pollen

Bee Pollen. Chemical Composition and Therapeutic Application (2015 (Poland)


Pine Pollen against viruses

 

Therapeutic Potential of Brassinosteroids in Biomedical and Clinical Research (2020)(India, China, Italy)


Immune system and Honey

Effect of honey on antibody production (2004) (Dubai)


Melittin against a broad spectrum of viruses 

Melittin: a venom-derived peptide with promising anti-viral properties – Hamed MemarianiMojtaba MemarianiHamideh MoravvejMohammad Shahidi-DadrasEuropean Journal of Clinical Microbiology & Infectious Diseases volume 39pages5–17(2020)


 

Chemical substances against viruses

Alcohol

Efficacy of ethanol against viruses in hand disinfection ((2018) (Germany)

Note from the editor:
Most of the propolis tinctures from the market are made with alcohol from 70 to 96%.

Their use in the form of pharyngeal (throat) spray and nebulization (after dilution with honey which is acidic and enriched with essential oils that have a broad antiviral spectrum, see above) is therefore recommended.

Even if the viruses are not completely destroyed (because the concentration of alcohol on the respiratory mucosas is lower than the one from the laboratory tests), the fact that they may be damaged in their structure and/or have their virulence decreased, may be very useful at least from the preventative point of view.


Organic acids against thrombosis (as fibrinolytic agents)
Several Beehive products (honey, honeydew honey, honey vinegar, bee pollen, bee bread, propolis and royal jelly contain also many different types of organic acids)

Organic acids for thrombus disease management. (2015) (China)


Essential oils

Antiviral essential oils (2020) (Algeria)


Co-morbidities, Co-infections and beehive products

Role of Propolis

Emerging Roles of Propolis Antioxidant, Cardioprotective, and Antiangiogenic Actions (2013)(Brazil)



Antiviral Medicinal Bee Plants and their extracts

 


Antiviral essential oils (2020) (Algeria)


Nigella sativa (black cumin) and honey against COVID-19 (2020)(Saudi Arabia, Egypt)


Nigella sativa compounds against Covid-19 (2020)(Algeria)


Nigella sativa, Anthemis hyalina and Citrus sinensis against coronavirus (2014) (Turkey)


Essential oils of aromatic plants with antibacterial, antifungal, antiviral, and cytotoxic properties (2009)(Switzerland)


Houttuynia cordata and quercetin against viruses (2016, Singapore)


Polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors


The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase


The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase


Torreya nucifera, apigenine, luteoline and quercetine against SARS virus (2010)(Korea)


Withanone and Caffeic Acid Phenethyl Ester against SARS CoV 2 (2020) (India, Japan)


Traditional Chinese medicine for COVID-19 treatment